Epidemiological investigation of MP pneumonia and you may RWE away from 2003 so you’re able to 2014

Epidemiological investigation of MP pneumonia and you may RWE away from 2003 so you’re able to 2014

Statistical investigation

All calculations were performed with SPSS V.14.0 (SPSS Inc.)parisons between groups were performed using the Student’s t-test, ? 2 test and Fisher’s exact test, and the data were expressed as mean±SD for continuous variables. A p value of <0.05 was considered statistically significant.

Results

The latest victims in today’s data had been 793 clients having MP pneumonia and 384 customers with RWE in data several months. Having epidemiological analysis, a total 793 people were utilized, since the found during the prior to now composed article.14 To possess medical evaluation involving the organizations, a total of 501 MP pneumonia customers that were acknowledge while in the brand new latest epidemics (241 circumstances inside 2007–2006, and you may 260 circumstances in 2011), and you can 384 patients which have RWE were analysed (figure step one). Inside studies months, the full number of acknowledge patients on all of our department are good overall 25 911 (but garden center people). There are everything 2100 accepted patients a year with some variations during the on a yearly basis.

Most of MP pneumonia customers got pursue-up months at the very least 36 months out-of history epidemic seasons from 2011, nevertheless go after-right up victims happy with our choice criteria have been 180 certainly 501 cases on MP pneumonia classification and you will 206 certainly 384 times in the RWE classification.

For the MP pneumonia clients, there had been obvious outbreaks from times during the 2003, 2006–2007 and you may 2011, which includes cases taking place throughout the interepidemic episodes. There have been apparently steady amounts of RWE times from year to year during the research period. There are no associated improved cases inside MP pneumonia crisis age except into the 2007 (shape 2). No MP pneumonia patient who was simply readmitted due to MP reinfection over the epidemics are observed while in the studies several months. Brand new mean decades and you can many years distribution have been comparable, plus the level age range was in fact dos–5 years of age in both communities (shape 3). In the seasonality away from both teams, MP pneumonia is commonplace in the coming down order out-of fall, june, cold temperatures and spring season, while you are customers with RWE was very commonplace inside fall, accompanied by springtime, cold weather and you may june (investigation perhaps not revealed).

Group and you may systematic qualities away from MP pneumonia and you can RWE organizations

Demographic, clinical and laboratory data in both groups are shown in table 1. The mean age and age distribution were similar in both groups as shown in figure 3 (5.4 years vs 5.6 years, p=0.312). Both groups had male predominance, and there were more males in the RWE group. As expected, cases with wheezing at presentation, the proportion of patients with history or family history of allergic diseases, and history of wheezing were higher in the RWE group. Recurrent wheezing after discharge was observed in 38 of 180 patients with MP pneumonia and 141 of the 206 patients with RWE (p<0.001).

In MP pneumonia patients, 52 of the total 501 patients (10.4%) had wheezing at presentation, 72 (14.4%) had a history of allergic diseases, 15 (3%) had RWE according to our definition and 40 (8%) had a family history http://www.datingranking.net/pl/datemyage-recenzja/ of allergic diseases. When we divided the MP pneumonia patients into two groups of patients with wheezing (n=52) and without wheezing (n=449), the patients with wheezing were younger (3.7 years vs 5.6 years, p<0.001) and had higher proportions of history allergic diseases and wheezing history and higher values of leucocyte count and eosinophil differential (table 2). Among the 52 MP pneumonia patients with wheezing at admission, 10 were patient with RWE, while 42 had no previous RWE history. Thus, in this study, 66% (10 of 15) of patients with RWE history presented with wheezing, while 8.6% of patients without RWE history (42 of 486) had wheezing at presentation. In a follow-up study of patients who visited two or more times after discharge, 13 (including 5 cases of RWE) of 21 MP pneumonia patients with initial wheezing and 25 (including 2 cases of RWE) of 159 MP pneumonia patients without wheezing had at least one wheezing episode after discharge (table 2). Although not all patients were followed-up, it was estimated that at least 31 of the total MP pneumonia patients (n=501, 6.2%) showed a recurrent wheezing after initial MP infection.

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